David Ishee has been working on a method to affordably alter the genetics of pure-bred dogs so that the diseases that come with the lack of genetic diversity can be removed.
Check him out on Netflix by watching the docuseries “Unnatural Selection” 

David Ishee YouTube channel: https://www.youtube.com/channel/UCftN…
Patreon: https://www.patreon.com/DavidIshee